Amantadine can be used to treat tremor and rigidity. It isn’t used very often and is unlikely to be prescribed alone. It's usually given with other drug treatments and can be used at all stages of Parkinson’s. Amantadine (Symmetrel) may help people with mild Parkinson's disease by raising the amount of dopamine that your brain cells can use, which leads to fewer symptoms. Methods. In this multi-center, double-blind, randomized, placebo-controlled, cross-over trial, 36 patients with Parkinson's disease and dyskinesias were randomized, and 62 interventions, which included amantadine (300 mg /day) or placebo treatment for 27 days, were analyzed. User Reviews for Amantadine to treat Parkinson's Disease. Also known as: Gocovri, Osmolex ER, Symmetrel. The following information is NOT intended to endorse drugs or recommend therapy. If you have Parkinson's disease, you have a lot of choices for treatment. There's no cure, but medicine and sometimes surgery can help. Medicine can often keep your symptoms in check for years. Living with Parkinson's. While living with PD can be challenging, there are many things you can do to maintain and improve your quality of life and live well with Parkinson's disease. Amantadine can be prescribed to relieve the symptoms of Parkinson's disease, although other treatments are often preferred. Parkinson's disease affects the way your brain co-ordinates the movements of your muscles. Amantadine will not work for colds, other types of flu, or other virus infections. Amantadine is also an antidyskinetic medicine. It is used to treat Parkinson's disease (sometimes called paralysis agitans or shaking palsy ) and its symptoms, including dyskinesia (sudden uncontrolled movements). Medical uses Parkinson's disease. Amantadine is used to treat Parkinson's disease, as well as parkinsonism syndromes. A 2003 Cochrane review concluded evidence was inadequate to support the use of amantadine for Parkinson's disease. Amantadine. Amantadine is a medication that is useful in treating some symptoms of Parkinson's disease. It may cause greater amounts of dopamine to be released in the brain.